Characterization of therapeutic mAb charge heterogeneity by iCIEF coupled to mass spectrometry (iCIEF–MS)
Author:
Affiliation:
1. Department of Chemistry Aalen University Aalen Germany
2. Department of Pharmaceutical and Medicinal Chemistry Friedrich Schiller University Jena Jena Germany
3. F. Hoffmann‐La Roche Ltd. Basel Switzerland
Publisher
Wiley
Subject
Clinical Biochemistry,Biochemistry,Analytical Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/elps.202200170
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4. Identification of multiple sources of charge heterogeneity in a recombinant antibody
5. C-terminal lysine variants in fully human monoclonal antibodies: Investigation of test methods and possible causes
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