T-cell diversification reflects antigen selection in the blood of patients on immune checkpoint inhibition and may be exploited as liquid biopsy biomarker

Author:

Akyüz Nuray1,Brandt Anna1,Stein Alexander1,Schliffke Simon1,Mährle Thorben1,Quidde Julia1,Goekkurt Eray2,Loges Sonja1,Haalck Thomas3,Ford Christopher Thomas1,Asemissen Anne Marie1,Thiele Benjamin1,Radloff Janina1,Thenhausen Toni4,Krohn-Grimberghe Artus45,Bokemeyer Carsten1,Binder Mascha1

Affiliation:

1. Department of Oncology and Hematology, BMT with section Pneumology; Hubertus Wald Tumorzentrum/UCCH, University Medical Center Hamburg-Eppendorf; Hamburg Germany

2. Hämatologisch-Onkologische Praxis Eppendorf (HOPE); Hamburg Germany

3. Department of Dermatology; Hubertus Wald Tumorzentrum/UCCH, University Medical Center Hamburg-Eppendorf; Hamburg Germany

4. LYTIQ GmbH; Paderborn Germany

5. Analytische Informationssysteme und Business Intelligence, Universität Paderborn; Paderborn Germany

Funder

Annemarie Hilgemann foundation

Hubertus Wald foundation

Publisher

Wiley

Subject

Cancer Research,Oncology

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