Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies

Author:

Wang Xu1,Tan Ziqiang2,Pan Yuanhu3,Ihsan Awais4,Liu Qianying3,Huang Lingli3,Cheng Guyue3,Chen Dongmei3,Tao Yanfei3,Liu Zhenli3,Yuan Zonghui123

Affiliation:

1. National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Wuhan, Hubei 430070, China

2. MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products; Huazhong Agricultural University; Wuhan Hubei 430070 China

3. Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety; Wuhan Hubei China

4. Department of Biosciences; COMSATS Institute of Information Technology; Sahiwal Pakistan

Funder

National Risk Assessment of Quality and Safety of Livestock and Poultry Products

National 863 Program of China

Publisher

Wiley

Subject

Toxicology

Reference37 articles.

1. Cytotoxic and genotoxic effects of in vitro exposure to triclosan and trimethoprim on zebra mussel (Dreissena polymorpha) hemocytes;Binelli;Comp. Biochem. Physiol. C Toxicol. Pharmacol. CBP,2009

2. Trimethoprim, a sulphonamide potentiator;Bushby;Br. J. Pharmacol. Chemother.,1968

3. Sulfa and trimethoprim-like drugs - antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors;Capasso;J. Enzyme Inhib. Med. Chem.,2014

4. EMEA 1997a Trimethoprim. Summary Report (2) (EMEA/MRL/255/97-FINAL) http://www.emea.europa.eu/pdfs/vet/mrls/025597en.pdf

5. EMEA 1997b Baquiloprim. Summary Report (2) (EMEA/MRL/199/97-FINAL) http://www.emea.eu.int/pdfs/vet/mrls/019997en.pdf

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