Affiliation:
1. Department of Medicine Lung Biology Center, Zuckerberg San Francisco General Hospital San Francisco California USA
2. Department of Medicine University of California San Francisco San Francisco California USA
3. Department of Medicine University of Colorado Anschutz Medical Campus Aurora Colorado USA
Abstract
AbstractWhether all Schistosoma species cause pulmonary hypertension (PH) is unclear. Experimentally exposing mice to Schistosoma haematobium eggs caused PH, which was less severe than that induced by S. mansoni exposure. These findings align with the relatively uncommon reports of pulmonary arterial hypertension associated with S. haematobium.
Funder
American Heart Association
Congressionally Directed Medical Research Programs
American Thoracic Society
Cardiovascular Medical Research and Education Fund
National Heart, Lung, and Blood Institute
United Therapeutics Corporation
Reference18 articles.
1. Schistosomiasis Pulmonary Arterial Hypertension
2. Schistosomiasis-associated pulmonary arterial hypertension: a systematic review
3. [Pulmonary arterial hypertension due to bilharziasis. Apropos of a case due to Schistosoma haematobium having been cured by praziquantel];Bourée P;Bull Soc Pathol Exot,1990
4. Cor pulmonale due to chronic infestation with Schistosoma haematobium;Damluji SF;J Trop Med Hyg,1964
5. Hepatic Shunting of Eggs and Pulmonary Vascular Remodeling inBmpr2+/−Mice with Schistosomiasis