Cardiopulmonary exercise testing and the 2022 definition of pulmonary hypertension

Author:

Habedank Dirk12ORCID,Ittermann Till3,Kaczmarek Sabine2,Stubbe Beate2ORCID,Heine Alexander2,Obst Anne2,Ewert Ralf2

Affiliation:

1. Clinical Medicine Department Cardiology DRK Kliniken Berlin Köpenick Berlin Germany

2. Department of Internal Medicine B—Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases University Medicine Greifswald Greifswald Germany

3. Department SHIP Clinical‐Epidemiological Research, Institute for Community Medicine University Medicine Greifswald Greifswald Germany

Abstract

AbstractParameters of cardiopulmonary exercise testing significantly discriminate between healthy subjects and patients with pulmonary hypertension (PH), also according to the new 2022 definition of pulmonary hypertension (mean pulmonary arterial pressure mPAP > 20 mmHg). The cut‐offs indicating on PH were peakVO2 ≤ 16.7 mL/min/kg (Youden‐Index YI = 0.79), petCO2@AT ≤ 34 mmHg (YI = 0.67), and VE/VCO2@AT ≤ 30 (YI = 0.76).

Funder

Pfizer

Siemens Healthineers

Novo Nordisk

Deutsche Forschungsgemeinschaft

GABA International

Publisher

Wiley

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