Plasma NEDD9 is increased following SARS‐CoV‐2 infection and associates with indices of pulmonary vascular dysfunction-Reference-Cited by-同舟云学术

Plasma NEDD9 is increased following SARS‐CoV‐2 infection and associates with indices of pulmonary vascular dysfunction

Published:2024-01 Issue:1 Volume:14 Page:
ISSN:2045-8940
Container-title:Pulmonary Circulation
language:en
Short-container-title:Pulm. circ.

Author:

Alba George A.¹²^ORCID,Zhou Iris Y.¹³⁴,Mascia Molly¹²,Magaletta Michael³,Alladina Jehan W.¹²,Giacona Francesca L.²,Ginns Leo C.¹²,Caravan Peter¹³⁴,Maron Bradley A.⁵⁶,Montesi Sydney B.¹²⁴

Affiliation:

1. Harvard Medical School Boston Massachusetts USA

2. Division of Pulmonary and Critical Care Medicine Massachusetts General Hospital Boston Massachusetts USA

3. Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Boston Massachusetts USA

4. Institute for Innovation in Imaging Massachusetts General Hospital Boston Massachusetts USA

5. Division of Cardiovascular Medicine Brigham and Women's Hospital Boston Massachusetts USA

6. Department of Medicine University of Maryland School of Medicine Baltimore Maryland USA

Abstract

AbstractCompared to healthy volunteers, participants with post‐acute sequelae of SARS‐CoV‐2 infection (PASC) demonstrated increased plasma levels of the prothrombotic protein NEDD9, which associated inversely with indices of pulmonary vascular function. This suggests persistent pulmonary vascular dysfunction may play a role in the pathobiology of PASC.

Funder

National Heart, Lung, and Blood Institute

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pul2.12356

Reference18 articles.

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2. Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome

3. Pulmonary endothelial NEDD9 and the prothrombotic pathophenotype of acute respiratory distress syndrome due to SARS‐CoV‐2 infection

4. Dynamic Contrast-enhanced MRI Demonstrates Pulmonary Microvascular Abnormalities Months After SARS-CoV-2 Infection

5. Dynamic contrast-enhanced magnetic resonance imaging of the lung reveals important pathobiology in idiopathic pulmonary fibrosis

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