Air travel in patients suffering from pulmonary hypertension—A prospective, multicentre study

Author:

Yogeswaran Athiththan1ORCID,Grimminger Jan1,Tello Khodr1,Becker Lukas1,Seeger Werner2ORCID,Grimminger Friedrich2,Sommer Natascha1,Ghofrani Hossein A.1ORCID,Lange Tobias J.34,Stadler Stefan5,Olsson Karen67,Kamp Jan C.67ORCID,Rosenkranz Stephan8,Gerhardt Felix8,Milger Katrin9,Barnikel Michaela9,Ulrich Silvia10,Saxer Stéphanie10,Grünig Ekkehard11,Harutynova Satenik11,Opitz Christian12,Klose Hans13,Wilkens Heinrike14,Halank Michael15,Heberling Melanie15ORCID,Gall Henning1ORCID,Richter Manuel J.1ORCID

Affiliation:

1. Department of Internal Medicine, Justus‐Liebig‐University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany

2. Department of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC) Institute for Lung Health (ILH), Cardio‐Pulmonary Institute (CPI), Member of the German Center for Lung Research (DZL) Giessen Germany

3. Department of Internal Medicine II, Pulmonology and Intensive Care Kreisklinik Bad Reichenhall Bad Reichenhall Germany

4. Department of Internal Medicine II, Faculty of Medicine Regensburg University Regensburg Germany

5. Department of Internal Medicine II University Medical Center Regensburg Regensburg Germany

6. Department of Respiratory Medicine and Infectious Diseases Hannover Medical School Hannover Germany

7. Member of the German Center for Lung Research (DZL) Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH) Hannover Germany

8. Klinik III für Innere Medizin Herzzentrum der Universität zu Köln Cologne Germany

9. Department of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center Member of the German Center for Lung Research (DZL) Giessen Germany

10. Department of Respiratory Medicine, Pulmonary Hypertension Unit University Hospital Zurich Zurich Switzerland

11. Thoraxklinik‐Heidelberg gGmbH German Center for Lung Research (DZL) Heidelberg Germany

12. Department of Cardiology DRK Kliniken Berlin Westend Berlin Germany

13. Department of Respiratory Medicine Eppendorf University Hospital Hamburg Germany

14. Klinik fur Innere Medizin V, Pneumologie Universitätsklinikum des Saarlandes Homburg Germany

15. Internal Medicine I—Department of Pneumology University Hospital Carl Gustav Carus of TU Dresden Germany

Abstract

AbstractThe PEGASUS study is the first multicentric and prospective assessment of the safety of air travel flying in pulmonary hypertension (PH) (NCT03051763). Data of air travel from 60 patients with PH was available. No severe adverse events occurred. Nine patients self‐reported mild adverse events during flight (13%), while after landing, 12 patients reported events (20%). Solely one patient (2%) had an adverse event leading to medical consultation. In patients with PH and World Health Organization functional classes II and III, air travel was safe.

Publisher

Wiley

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