SH2B1 promotes epithelial-mesenchymal transition through the IRS1/β-catenin signaling axis in lung adenocarcinoma

Author:

Wang Shaoqiang1,Cheng Yuanda2,Gao Yang2,He Zhiwei2,Zhou Wolong2,Chang Ruimin2,Peng Zhenzi3,Zheng Yingying4,Duan Chaojun3,Zhang Chunfang2ORCID

Affiliation:

1. Department of Thoracic Surgery; Affiliated Hospital of Jining Medical College; Jining Medical College; Jining Shandong P.R. China

2. Department of Thoracic Surgery; Xiangya Hospital; Central South University; Changsha Hunan P.R. China

3. Institute of Medical Sciences; Key Laboratory of Cancer Proteomics of Chinese Ministry of Health; Xiangya Hospital; Central South University; Changsha Hunan P.R. China

4. Department of Endocrinology; Affiliated Hospital of Jining Medical College; Jining Medical College; Jining Shandong P.R. China

Funder

Key Research and Development Program of Hunan Province

National Natural Science Foundation of China

Science Funds for Young Scholar of Xiangya Hospital

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference65 articles.

1. Cancer statistics, 2015;Siegel;CA: Cancer J Clin,2015

2. Cancer statistics in China, 2015;Chen;CA: Cancer J Clin,2016

3. The global burden of cancer 2013;Fitzmaurice;JAMA Oncol,2015

4. Curbing the burden of lung cancer;Urman;Front Med,2016

5. Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma;Bronte;Cancer Treatment Rev,2010

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