A gene variant of PNPLA3 , but not of APOC3 , is associated with histological parameters of NAFLD in an obese population

Author:

Verrijken A.1,Beckers S.2,Francque S.3,Hilden H.4,Caron S.5678,Zegers D.2,Ruppert M.9,Hubens G.9,Van Marck E.10,Michielsen P.3,Staels B.5678,Taskinen M.-R.4,Van Hul W.2,Van Gaal L.1

Affiliation:

1. Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital; University of Antwerp; Belgium

2. Department of Medical Genetics; University of Antwerp; Belgium

3. Department of Gastroenterology and Hepatology; Antwerp University Hospital; University of Antwerp; Belgium

4. Division of Cardiology; Department of Medicine; Helsinki University Central Hospital and Biomedicum; Finland

5. Université Lille Nord de France; Lille France

6. INSERM U1011; Lille France

7. UDSL; Lille France

8. Institut Pasteur de Lille; Lille France

9. Department of Abdominal Surgery; Antwerp University Hospital; University of Antwerp; Belgium

10. Department of Pathology; Antwerp University Hospital; University of Antwerp; Belgium

Funder

European Commission as an Integrated Project under the 6th Framework Program

Publisher

Wiley

Subject

Nutrition and Dietetics,Endocrinology,Endocrinology, Diabetes and Metabolism,Medicine (miscellaneous)

Reference40 articles.

1. The emerging epidemic of obesity in developing countries;Prentice;Int J Epidemiol,2007

2. Nonalcoholic fatty liver disease;Angulo;N Engl J Med,2002

3. Pathological features of NASH;Brunt;Front Biosci,2005

4. Nonalcoholic fatty liver disease: pathology and pathogenesis;Tiniakos;Annu Rev Pathol,2010

5. Nonalcoholic fatty liver disease in Asia: firmly entrenched and rapidly gaining ground;Chitturi;J Gastroenterol Hepatol,2011

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