Validated UPLC-MS/MS method for quantification of seven compounds in rat plasma and tissues: Application to pharmacokinetic and tissue distribution studies in rats after oral administration of extract ofEclipta prostrataL.

Author:

Du Guangyan1,Fu Lingling1,Jia Jun2,Pang Xu1,Yu Haiyang1,Zhang Youcai3,Fan Guanwei14,Gao Xiumei1,Han Lifeng1ORCID

Affiliation:

1. Tianjin State Key Laboratory of Modern Chinese Medicine; Nankai District Tianjin People's Republic of China

2. Department of Surgery of Foot and Ankle, Tianjin Hospital; Hexi District Tianjin People's Republic of China

3. School of Pharmaceutical Science and Technology; Tianjin University; Nankai District Tianjin People's Republic of China

4. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; Nankai District Tianjin People's Republic of China

Funder

National Key Technology R&D Program of China

Special Scientific Research for Traditional Chinese Medicine of State Administration of Traditional Chinese Medicine of China

Key Program for National Natural Science Foundation of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

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