Effects of long‐acting analogues of lamprey GLP‐1 and paddlefish glucagon on alpha‐ to beta‐cell transdifferentiation in an insulin‐deficient transgenic mouse model-Reference-Cited by-同舟云学术

Effects of long‐acting analogues of lamprey GLP‐1 and paddlefish glucagon on alpha‐ to beta‐cell transdifferentiation in an insulin‐deficient transgenic mouse model

Published:2021-04-11 Issue:8 Volume:27 Page:
ISSN:1075-2617
Container-title:Journal of Peptide Science
language:en
Short-container-title:J Pep Sci

Author:

Graham Galyna V.¹,Conlon J. Michael¹^ORCID,Moffett R. Charlotte¹^ORCID,Abdel‐Wahab Yasser H.¹^ORCID,Flatt Peter R.¹^ORCID

Affiliation:

1. Diabetes Research Group, School of Biomedical Sciences Ulster University Cromore Road Coleraine BT52 1SA UK

Funder

Department of Education and Learning, Northern Ireland

Publisher

Wiley

Subject

Organic Chemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psc.3328

Reference29 articles.

1. Novel dual agonist peptide analogues derived from dogfish glucagon show promising in vitro insulin releasing actions and antihyperglycaemic activity in mice

3. Glucagon-like peptides-1 from phylogenetically ancient fish show potent anti-diabetic activities by acting as dual GLP1R and GCGR agonists

4. Dogfish glucagon analogues counter hyperglycaemia and enhance both insulin secretion and action in diet-induced obese diabetic mice

5. Glucagon from the phylogenetically ancient paddlefish provides a template for the design of a long-acting peptide with effective anti-diabetic and anti-obesity activities

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