Transforming growth factor β signaling pathway: A promising therapeutic target for cancer-Reference-Cited by-同舟云学术

Transforming growth factor β signaling pathway: A promising therapeutic target for cancer

Published:2019-07-22 Issue:3 Volume:235 Page:1903-1914
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J Cell Physiol

Author:

Chen Yuhong¹²³⁴,Di Cuixia¹²³⁴,Zhang Xuetian¹²³⁴,Wang Jing⁵,Wang Fang¹²³⁴,Yan Jun‐fang¹²³⁴,Xu Caipeng¹²³⁴,Zhang Jinhua¹²³⁴,Zhang Qianjing¹²³⁴,Li Hongyan¹²³⁴,Yang Hongying⁶,Zhang Hong¹²³⁴^ORCID

Affiliation:

1. Department of Radiation Medicine, Institute of Modern Physics Chinese Academy of Sciences Lanzhou China

2. Key Laboratory of Heavy Ion Radiation Biology and Medicine Chinese Academy of Sciences Lanzhou China

3. College of Life Sciences University of Chinese Academy of Sciences Beijing China

4. School of Nuclear Science and Technology University of Chinese Academy of Sciences Beijing China

5. School of Basic Medical Sciences Lanzhou University Lanzhou China

6. Medical College of Soochow University Soochow University Suzhou China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.29108

Reference116 articles.

1. TGF- β signaling in cancer – a double-edged sword

2. Targeting the TGFβ signalling pathway in disease

3. The TGFβ pathway stimulates ovarian cancer cell proliferation by increasing IGF1R levels

4. Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta.

5. Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer progression.

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