Rapid Prototyping of Concave Microwells for the Formation of 3D Multicellular Cancer Aggregates for Drug Screening-Reference-Cited by-同舟云学术

Rapid Prototyping of Concave Microwells for the Formation of 3D Multicellular Cancer Aggregates for Drug Screening

Published:2013-08-27 Issue:4 Volume:3 Page:609-616
ISSN:2192-2640
Container-title:Advanced Healthcare Materials
language:en
Short-container-title:Adv. Healthcare Mater.

Author:

Tu Ting-Yuan¹,Wang Zhe¹,Bai Jing¹,Sun Wei¹,Peng Weng Kung¹,Huang Ruby Yun-Ju²,Thiery Jean-Paul³,Kamm Roger D.¹⁴

Affiliation:

1. BioSystems and Micromechanics IRG; Singapore-MIT Alliance for Research and Technology (SMART) Center; 1 CREATE Way, #04-13/14 Enterprise, Wing Singapore 138602 Singapore

2. Cancer Science Institute of Singapore; National University of Singapore; MD6, Medical Drive Singapore 117456 Singapore

3. Institute of Molecular Cell Biology (IMCB), A-STAR, Department of Biochemistry School of Medicine; National University of Singapore, Proteos; 61 Biopolis Drive Singapore 138673 Singapore

4. Department of Biological Engineering and Department of Mechanical Engineering; Massachusetts Institute of Technology; Cambridge MA 02139 USA

Publisher

Wiley

Subject

Pharmaceutical Science,Biomedical Engineering,Biomaterials

Reference48 articles.

1. Potential and Bottlenecks of Bioreactors in 3D Cell Culture and Tissue Manufacturing

2. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion

3. Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11

4. Collective cell migration in morphogenesis, regeneration and cancer

5. Engineered 3D environments to elucidate the effect of environmental parameters on drug response in cancer

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