VKORC1andCYP2C9genotypes are predictors of warfarin-related outcomes in children

Author:

Shaw Kaitlyn12,Amstutz Ursula12,Hildebrand Claudette2,Rassekh S. Rod3,Hosking Martin4,Neville Kathleen5,Leeder J. Steven6,Hayden Michael R.7,Ross Colin J.17,Carleton Bruce C.12

Affiliation:

1. Department of Pediatrics; Faculty of Medicine; University of British Columbia (UBC); Vancouver BC Canada

2. Pharmaceutical Outcomes Programme; B.C. Children's Hospital; Vancouver BC Canada

3. Division of Pediatric Hematology/Oncology/BMT; B.C. Children's Hospital; Vancouver BC Canada

4. Division of Pediatric Cardiology; B.C. Children's Hospital; Vancouver BC Canada

5. Division of Pediatric Hematology/Oncology; Children's Mercy Hospitals and Clinics; Kansas City Missouri

6. Division of Clinical Pharmacology and Medical Toxicology; Children's Mercy Hospitals and Clinics; Kansas City Missouri

7. Centre for Molecular Medicine and Therapeutics; UBC; Vancouver BC Canada

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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1. La pharmacothérapie en fonction des gènes;Paediatrics & Child Health;2023-06-06

2. Gene-based drug therapy in children;Paediatrics & Child Health;2023-06-06

3. A Systematic Review of Polygenic Models for Predicting Drug Outcomes;Journal of Personalized Medicine;2022-08-27

4. Genotype‐guided warfarin therapy: Still of only questionable value two decades on;Journal of Clinical Pharmacy and Therapeutics;2020-03-13

5. CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis;The Pharmacogenomics Journal;2019-11-01

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