Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions-Reference-Cited by-同舟云学术

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Rigidity of the extracellular part of HER2: Evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions

Published:2017-07-05 Issue:9 Volume:26 Page:1796-1806
ISSN:0961-8368
Container-title:Protein Science
language:en
Short-container-title:Protein Science

Author:

Jost Christian¹,Stüber Jakob C.¹^ORCID,Honegger Annemarie¹,Wu Yufan¹,Batyuk Alexander¹,Plückthun Andreas¹^ORCID

Affiliation:

1. Department of Biochemistry; University of Zurich; 8057 Zurich Switzerland

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Chemiefonds fellowship of the Verband der Chemischen Industrie

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/pro.3216/fullpdf

Reference32 articles.

1. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3;Baselga;Nat Rev Cancer,2009

2. Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor;Mi;Nat Struct Mol Biol,2011

3. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab;Cho;Nature,2003

4. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex;Franklin;Cancer Cell,2004

5. The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors;Garrett;Mol Cell,2003

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1. An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity;Nature Communications;2023-03-13

2. Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization;Communications Biology;2021-06-21

3. Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action;Nature Communications;2021-06-18

4. Repeat proteins: designing new shapes and functions for solenoid folds;Current Opinion in Structural Biology;2021-06

5. Remote control of magnetic nanocomplexes for delivery and destruction of cancer cells;Journal of Biomaterials Applications;2021-04-12

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