Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report

Author:

Sato Yudai1ORCID,Tadokoro Tomoko1,Yamana Hiroki1,Akai Hiraki1,Takuma Kei1,Fujita Naoki1,Nakahara Mai1,Oura Kyoko1,Fujita Koji1,Tani Joji1,Kamada Hideki1,Morishita Asahiro1,Kobara Hideki1,Kagawa Seiko2,Haba Reiji2,Okano Keiichi3,Masaki Tsutomu1

Affiliation:

1. Department of Gastroenterology and Neurology Kagawa University Kagawa Japan

2. Department of Pathology Kagawa University Kagawa Japan

3. Department of Gastroenterological Surgery Kagawa University Kagawa Japan

Abstract

AbstractHepatocellular carcinoma invasion of the bile duct is rare and has a poor prognosis. A 77‐year‐old man presented at the emergency department with persistent pain in the right hypochondrium. Blood tests and imaging studies revealed a 70‐mm occupying lesion in the right lobe of the liver and dilated intrahepatic bile ducts. He was diagnosed with obstructive jaundice and cholangitis. Imaging studies showed an internal mass with poor contrast effects. A liver biopsy was performed to confirm the diagnosis and hepatocellular carcinoma was suspected. Endoscopic retrograde cholangiopancreatography, endoscopic ultrasound, and peroral cholangioscopy were performed to determine the treatment strategy. The bile duct invasion did not extend to the porta hepatis; therefore, right hepatic lobectomy and radical resection were performed. Bile duct invasion in hepatocellular carcinoma is rare and often difficult to diagnose by computed tomography or conventional endoscopic retrograde cholangiopancreatography. However, endoscopic ultrasound and peroral cholangioscopy enable safe and accurate diagnosis of the extent of invasion.

Publisher

Wiley

Subject

Organic Chemistry,Biochemistry

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