An LC–MS/MS method for determination of O 6 ‐benzylguanine and its metabolite O 6 ‐benzyl‐8‐oxoguanine in human plasma-Reference-Cited by-同舟云学术

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An LC–MS/MS method for determination of O 6 ‐benzylguanine and its metabolite O 6 ‐benzyl‐8‐oxoguanine in human plasma

Published:2020-01-06 Issue:2 Volume:34 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Mannem Chandana¹,Xu Yan¹²^ORCID

Affiliation:

1. Department of ChemistryCleveland State University Cleveland OH USA

2. Case Comprehensive Cancer CenterCase Western Reserve University Cleveland OH USA

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4750

Reference17 articles.

1. Phase I Clinical Trial of O6-Benzylguanine and Topical Carmustine in the Treatment of Cutaneous T-Cell Lymphoma, Mycosis Fungoides Type

2. Pharmacokinetics of O6‐benzylguanine and its active metabolite 8‐oxo‐O6‐benzylguanine in plasma and cerebrospinal fluid after intrathecal administration of O6‐benzylguanine in the nonhuman primate;Berg S. L.;Clinical Cancer Research,1998

3. Inactivation of O 6-alkylguanine-DNA alkyltransferase by 8-substituted O 6-benzylguanine analogs in mice

4. O6-Alkylguanine-DNA alkyltransferase activity of human malignant glioma and its clinical implications

5. Drug Resistance in Cancer: An Overview

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