A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice
Author:
Affiliation:
1. Sanford Burnham Prebys Medical Discovery Institute; La Jolla CA
2. The University of Texas M.D. Anderson Cancer Center; Houston TX
3. Mayo Clinic; Rochester MN
Funder
Mayo Clinic Cancer Center
SBP NCI Cancer Center
Publisher
Wiley
Subject
Hepatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.28468/fullpdf
Reference34 articles.
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3. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension;Wang;Proc Natl Acad Sci U S A,1995
4. HIF-1α is essential for myeloid cell-mediated inflammation;Cramer;Cell,2003
5. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation;Jaakkola;Science,2001
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