Targeted STAT1 therapy for LZTR1‐driven peripheral nerve sheath tumor
Author:
Affiliation:
1. VIB‐KU Leuven Center for Cancer Biology VIB Leuven Belgium
2. Nuclear Medicine and Molecular Imaging Department of Imaging and Pathology KU Leuven Leuven Belgium
3. Biomedical MRI Department of Imaging and Pathology KU Leuven Leuven Belgium
Funder
H2020 European Research Council
Publisher
Wiley
Subject
Cancer Research,Oncology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cac2.12490
Reference10 articles.
1. Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination
2. LZTR1Mutation Mediates Oncogenesis through Stabilization of EGFR and AXL
3. The molecular pathogenesis of schwannomatosis, a paradigm for the co-involvement of multiple tumour suppressor genes in tumorigenesis
4. Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
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