Affiliation:
1. Dermatology Unit San Marco Veterinary Clinic and Laboratory Veggiano Italy
2. Dermatopathology Unit San Marco Veterinary Clinic and Laboratory Veggiano Italy
3. Dermatology Unit Department of Medicine (DIMED) University of Padua Padua Italy
Abstract
AbstractWe describe 20 cases of canine pyoderma responsive to immunosuppressive treatments and resembling human pyoderma gangrenosum. All dogs presented with a rapidly evolving, focal to multifocal, painful ulcerative dermatitis, non‐responsive to multiple antibiotic and anti‐inflammatory therapies. Elevations of C‐reactive protein (100%), neutrophilia (75%) and fever (25%) were also present. Histopathology showed a severe, ulcerative, superficial to deep, predominantly neutrophilic dermatitis. Bacterial infection was the most challenging differential diagnosis. Resolution of the lesions was obtained within 4–8 weeks in 83% of dogs treated with ciclosporin. Maintenance treatment was required in the majority of the dogs.