Pericentral hepatocytes produce insulin-like growth factor-2 to promote liver regeneration during selected injuries in mice

Author:

Liu Junlai123,Hu Xiao2,Chen Jie4,Li Xinqi123,Wang Lu1,Wang Binbin123,Peng Wenbo123,Yang Cuiwei123,Li Zhijie123,Chen Yan5,Wang Yue J.6,Li Chuanjiang5,Li Xiajun1,Yan Fang7,Wang Yunfang7,Shang Changzhen4,Wang Xin8910,Chen Tao4,Huang Pengyu1

Affiliation:

1. School of Life Science and Technology; ShanghaiTech University; Shanghai China

2. Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences; Chinese Academy of Sciences; Shanghai China

3. University of Chinese Academy of Sciences; Beijing China

4. Department of Hepatobiliary Surgery, Sun Yat-sen Memorial Hospital; Sun Yat-sen University; Guangzhou China

5. Department of Hepatobiliary Surgery, Nanfang Hospital; Southern Medical University; Guangzhou China

6. Department of Medicine, Division of Gastroenterology; University of Pennsylvania; Philadelphia PA

7. Stem Cell and Tissue Engineering Lab; Beijing Institute of Transfusion Medicine; Beijing China

8. The Key Laboratory of National Education Ministry for Mammalian Reproductive Biology and Biotechnology; Inner Mongolia University; Huhhot P.R. China

9. Department of Laboratory Medicine and Pathology; University of Minnesota; Minneapolis Minnesota, MN

10. Hepatoscience Incorporation; Sunnyvale CA

Funder

Ministry of Science and Technology of China

National Key Research and Development Program of China

Science and Technology Planning Project of Guangdong China

Science and Technology Program of Guangzhou, China (STPG)

Publisher

Wiley

Subject

Hepatology

Reference27 articles.

1. Regeneration of liver parenchyma under normal and pathological conditions;Stocker;Beitr Pathol,1971

2. Liver regeneration;Michalopoulos;Science,1997

3. Liver regeneration-mechanisms and models to clinical application;Forbes;Nat Rev Gastroenterol Hepatol,2016

4. Induction of early-immediate genes by tumor necrosis factor alpha contribute to liver repair following chemical-induced hepatotoxicity;Bruccoleri;Hepatology,1997

5. Animal models of liver regeneration;Palmes;Biomaterials,2004

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