Projections of costs and quality adjusted life years lost due to dementia from 2020 to 2050: A population‐based microsimulation study

Author:

Brück Chiara C.1ORCID,Wolters Frank J.23,Ikram Mohammad Arfan2,de Kok Inge M. C. M.1

Affiliation:

1. Department of Public Health Erasmus MC Rotterdam The Netherlands

2. Department of Epidemiology Erasmus MC Rotterdam The Netherlands

3. Department of Radiology & Nuclear Medicine and Alzheimer Center Erasmus MC Rotterdam The Netherlands

Abstract

AbstractIntroductionEfficient healthcare planning requires reliable projections of the future increase in costs and quality‐adjusted life years (QALYs) lost due to dementia.MethodsWe used the microsimulation model MISCAN‐Dementia to simulate life histories and dementia occurrence using population‐based Rotterdam Study data and nationwide birth cohort demographics. We estimated costs and QALYs lost in the Netherlands from 2020 to 2050, incorporating literature estimates of cost and utility for patients and caregivers by dementia severity and care setting.ResultsSocietal costs and QALYs lost due to dementia are estimated to double between 2020 and 2050. Costs are incurred predominantly through institutional (34%), formal home (31%), and informal home care (20%). Lost QALYs are mostly due to shortened life expectancy (67%) and, to a lesser extent, quality of life with severe dementia (14%).DiscussionTo limit healthcare costs and quality of life losses due to dementia, interventions are needed that slow symptom progression and reduce care dependency.

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Reference47 articles.

1. PattersonC.World Alzheimer report 2018. The state of the art of dementia research: New frontiers.2018.

2. World Alzheimer Report 2015: the global impact of dementia: an analysis of prevalence, incidence, cost and trends. 2015;Prince MJ;Alzheimer's Disease International

3. Is dementia incidence declining?: Trends in dementia incidence since 1990 in the Rotterdam Study

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