Validation of Excised Bovine Nasal Mucosa as In Vitro Model to Study Drug Transport and Metabolic Pathways in Nasal Epithelium‡‡Data adopted from yet unpublished parts of the Ph.D. theses of Günter Ditzinger, Steffen Lang, and M. Christiane Schmidt-Reference-Cited by-同舟云学术

Validation of Excised Bovine Nasal Mucosa as In Vitro Model to Study Drug Transport and Metabolic Pathways in Nasal Epithelium‡‡Data adopted from yet unpublished parts of the Ph.D. theses of Günter Ditzinger, Steffen Lang, and M. Christiane Schmidt

Published:2000-03 Issue:3 Volume:89 Page:396-407
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Schmidt M. Christiane,Simmen Daniel,Hilbe Monika,Boderke Peter,Ditzinger Günter,Sandow Jürgen,Lang Steffen,Rubas Werner,Merkle Hans P.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference29 articles.

1. Nasal systemic drug delivery;Chien,1989

2. In vitro cell models to study nasal mucosal permeability and metabolism;Schmidt;Adv Drug Deliv Rev,1998

3. Translocation of human calcitonin in respiratory nasal epithelium is associated with self‐assembly in lipid membrane;Schmidt;Biochemistry,1998

4. Proteolysis of human calcitonin in excised bovine nasal mucosa: elucidation of the metabolic pathway by liquid secondary ionization mass spectrometry (LSIMS) and matrix assisted laser desorption ionization mass spectrometry (MALDI);Lang;Pharm Res,1996

5. Schmidt MC, Rubas W, Merkle HP. Nasal epithelial permeation of thymotrinin(TP3) and thymocartin (TP4): competitive metabolism and self‐enhancement. Pharm Res, in press.

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