Two cases of life-threatening arrhythmia induced by risperidone: evaluation of risperidone and 9-hydroxy-risperidone concentrations

Author:

Ito Asami1ORCID,Enokiya Tomoyuki2,Kawamoto Eiji1,Iwashita Yoshiaki1,Takeda Taichi1,Ikemura Kenji2,Okuda Masahiro2,Imai Hiroshi1

Affiliation:

1. Emergency and Critical Care Center; Mie University Hospital; Tsu Japan

2. Department of Pharmacy; Mie University Hospital; Tsu Japan

Publisher

Wiley

Reference10 articles.

1. FD Public Health Advisory: Deaths with antipsychotics in elderly patients with behavioral disturbances http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm053171.htm

2. The antipsychotic story: changes in prescriptions and overdose without better safety;Berling;Br. J. Clin. Pharmacol.,2016

3. Risperidone-induced QT prolongation following overdose correlates with serum drug concentration and resolves rapidly with no evidence of altered pharmacokinetics;Pollak;J. Clin. Pharmacol.,2011

4. Serum and urine risperidone concentrations in an acute overdose;Lee;J. Clin. Psychopharmacol.,1997

5. An overdose of risperidone;Springfield;J. Anal. Toxicol.,1996

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