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Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins

  • Published:2017-02 Issue:2 Volume:32 Page:203-207
  • ISSN:0885-3185
  • Container-title:Movement Disorders
  • language:en
  • Short-container-title:Mov Disord.

Author:

Olanow C. Warren12,Kordower Jeffrey H.34

Affiliation:

1. Departments of Neurology and Neuroscience; Mount Sinai School of Medicine; New York 10029 New York USA

2. Clintrex LLC

3. Department of Neurological Sciencs; Rush University Schoolf of Medicine; Chicago Illinois USA

4. Van Andel Research Institute; Grands Rapids Michigan 60612 USA

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference47 articles.

1. First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers;Schenk;Mov Disord,2016

2. Is Parkinson's disease a prion disorder?;Olanow;Proc Natl Acad Sci U S A,2009

3. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease;Polymeropoulos;Science,1997

4. alpha-Synuclein locus triplication causes Parkinson's disease;Singleton;Science,2003

5. Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system;Kirik;J Neurosci,2002

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