Potent Antiproliferative Effects of 25-Hydroxy-16-ene-23-yne-vitamin D3That Resists the Catalytic Activity of Both CYP27B1 and CYP24A1-Reference-Cited by-同舟云学术

Potent Antiproliferative Effects of 25-Hydroxy-16-ene-23-yne-vitamin D3That Resists the Catalytic Activity of Both CYP27B1 and CYP24A1

Published:2014-06-17 Issue:8 Volume:115 Page:1392-1402
ISSN:0730-2312
Container-title:Journal of Cellular Biochemistry
language:en
Short-container-title:J. Cell. Biochem.

Author:

Rhieu Steve Y.¹,Annalora Andrew J.²,LaPorta Erika³,Welsh JoEllen³,Itoh Toshimasa⁴,Yamamoto Keiko⁴,Sakaki Toshiyuki⁵,Chen Tai C.⁶,Uskokovic Milan R.⁷,Reddy G. Satyanarayana¹

Affiliation:

1. Epimer LLC; North Smithfield Rhode Island 02896 USA

2. Department of Environmental and Molecular Toxicology; Oregon State University; Corvallis Oregon 97331 USA

3. Cancer Research Center and Departments of Biomedical Sciences and Environmental Health Sciences; University at Albany; Rensselaer New York 12144 USA

4. Laboratory of Drug Design and Medicinal Chemistry; Showa Pharmaceutical University; Tokyo Japan

5. Department of Biotechnology; Faculty of Engineering; Toyama Prefectural University; Imizu Japan

6. School of Medicine; Boston University; Boston Massachusetts 02118 USA

7. Hoffmann-La Roche Inc.; Nutley New Jersey 07110 USA

Funder

Epimer, LLC

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference63 articles.

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3. Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity;Annalora;Arch Biochem Biophys,2004

4. The crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism;Annalora;J Mol Biol,2010

5. Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme;Beckman;Biochemistry,1996

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