Exposure to MnCl2 · 4H2O during development induces activation of microglial and perivascular macrophage populations in the hippocampal dentate gyrus of rats

Author:

Abe Hajime12,Ohishi Takumi13,Nakane Fumiyuki1,Shiraki Ayako12,Tanaka Takeshi12,Yoshida Toshinori1,Shibutani Makoto1

Affiliation:

1. Laboratory of Veterinary Pathology; Tokyo University of Agriculture and Technology; 3-5-8 Saiwai-cho, Fuchu-shi Tokyo 183-8509 Japan

2. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences; Gifu University; 1-1 Yanagido, Gifu-shi Gifu 501-1193 Japan

3. Gotemba Laboratory; Bozo Research Center Inc.; 1284 Kamado Gotemba-shi Shizuoka 412-0039 Japan

Funder

Ministry of Health, Labour and Welfare of Japan

Publisher

Wiley

Subject

Toxicology

Reference34 articles.

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2. Manganese potentiates nitric oxide production by microglia;Chang;Brain Res. Mol. Brain Res.,1999

3. Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1;Damoiseaux;Immunology,1994

4. Manganese neurotoxicity;Dobson;Ann. NY Acad. Sci.,2004

5. Neurotoxicity of manganese chloride in neonatal and adult CD rats following subchronic (21-day) high-dose oral exposure;Dorman;J. Appl. Toxicol.,2000

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