Higher-than-expected population prevalence of potentially pathogenic germlineTP53variants in individuals unselected for cancer history-Reference-Cited by-同舟云学术

Higher-than-expected population prevalence of potentially pathogenic germlineTP53variants in individuals unselected for cancer history

Published:2017-09-21 Issue:12 Volume:38 Page:1723-1730
ISSN:1059-7794
Container-title:Human Mutation
language:en
Short-container-title:Human Mutation

Author:

de Andrade Kelvin César¹²^ORCID,Mirabello Lisa¹,Stewart Douglas R.¹,Karlins Eric³,Koster Roelof⁴,Wang Mingyi³,Gapstur Susan M.⁵,Gaudet Mia M.⁵,Freedman Neal D.⁶,Landi Maria Teresa⁷,Lemonnier Nathanaël⁸,Hainaut Pierre⁸,Savage Sharon A.¹,Achatz Maria Isabel¹

Affiliation:

1. Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics; National Cancer Institute, National Institutes of Health; Department of Health and Human Services; Bethesda Maryland USA

2. International Research Center; A.C. Camargo Cancer Center; São Paulo Brazil

3. Cancer Genomics Research Laboratory; Division of Cancer Epidemiology and Genetics; National Cancer Institute; Leidos Biomedical Research Inc.; Department of Health and Human Services; Bethesda Maryland USA

4. Laboratory of Genetic Susceptibility, Division of Cancer Epidemiology and Genetics; National Cancer Institute; National Institutes of Health; Department of Health and Human Services; Bethesda Maryland USA

5. Epidemiology Research Program; American Cancer Society; Atlanta Georgia USA

6. Metabolic Epidemiology Branch, Division of Cancer Epidemiology and Genetics; National Cancer Institute, National Institutes of Health; Department of Health and Human Services; Bethesda Maryland USA

7. Integrative Tumor Epidemiology Branch, Division of Cancer Epidemiology and Genetics; National Cancer Institute, National Institutes of Health; Department of Health and Human Services; Bethesda Maryland USA

8. Institute for Advanced Biosciences, Inserm U 1209 CNRS UMR 5309; Université Grenoble Alpes; Allée des Alpes La Tronche France

Funder

Division of Cancer Epidemiology and Genetics

National Cancer Institute

National Institutes of Health

Publisher

Wiley

Subject

Genetics(clinical),Genetics

Reference39 articles.

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2. The inherited p53 mutation in the Brazilian population;Achatz;Cold Spring Harbor Perspectives in Medicine,2016

3. Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families;Birch;Cancer Research,1994

4. TP53 variations in human cancers: New lessons from the IARC TP53 database and genomics data;Bouaoun;Human Mutation,2016

5. Impact of the MDM2 SNP309 and p53 Arg72Pro polymorphism on age of tumour onset in Li-Fraumeni syndrome;Bougeard;Journal of Medical Genetics,2006

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