The Flavonoid 7,4′-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts

Author:

Liu Changda1,Yang Nan1,Chen Xiaoke12,Tversky Jody3,Zhan Jixun4,Chehade Mirna1,Miller Rachel L.567,Li Xiu-Min1

Affiliation:

1. Department of Pediatric Allergy and Immunology; Icahn School of Medicine at Mount Sinai; New York NY 10029 USA

2. Respiratory Department; The Eighth Affiliated Hospital, Sun Yat-sen University; Shenzhen 518033 China

3. Division of Allergy and Clinical Immunology, Department of Medicine; Johns Hopkins University School of Medicine; Baltimore MD 21224 USA

4. Department of Biological Engineering; Utah State University; 4105 Old Main Hill Logan UT 84322 USA

5. Division of Pulmonary, Allergy, Critical Care, Department of Medicine; Columbia University; New York NY 10032 USA

6. Division of Allergy, Immunology and Rheumatology, Department of Pediatrics; Columbia University; New York NY 10032 USA

7. Department of Environmental Health Sciences; Columbia University; New York NY 10032 USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology

Reference36 articles.

1. From airway inflammation to inflammatory bowel disease: eotaxin-1, a key regulator of intestinal inflammation;Adar;Clin Immunol,2014

2. Histone deacetylation: an important mechanism in inflammatory lung diseases;Adcock;COPD,2005

3. An overlook to the characteristics and roles played by eotaxin network in the pathophysiology of food allergies: allergic asthma and atopic dermatitis;Ahmadi;Inflammation,2016

4. Corticosteroids: the drugs to beat;Barnes;Eur J Pharmacol,2006

5. Histone deacetylase-2 and airway disease;Barnes;Ther Adv Respir Dis,2009

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