Mechanistic modeling, simulation, and optimization of mixed‐mode chromatography for an antibody polishing step-Reference-Cited by-同舟云学术

Mechanistic modeling, simulation, and optimization of mixed‐mode chromatography for an antibody polishing step

Published:2022-12-25 Issue:2 Volume:39 Page:
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnology Progress

Author:

Hahn Tobias¹^ORCID,Geng Nora¹,Petrushevska‐Seebach Katerina²,Dolan Michael E.³,Scheindel Marcus⁴,Graf Pia¹,Takenaka Kosuke²,Izumida Kyo⁵,Li Lijuan³,Ma Zijian³,Schuelke Norbert³

Affiliation:

1. GoSilico GmbH Karlsruhe Germany

2. Takeda Pharmaceuticals Vienna Austria

3. Takeda Pharmaceuticals Lexington Massachusetts USA

4. Takeda Pharmaceuticals Orth an der Donau Austria

5. Takeda Pharmaceuticals Fujisawa Kanagawa Japan

Publisher

Wiley

Subject

Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3316

Reference40 articles.

1. Downstream Processing of Monoclonal Antibodies: Current Practices and Future Opportunities

2. Multimodal Chromatography for Purification of Biotherapeutics – A Review

3. Application of mixed mode resins for the purification of antibodies

4. Evaluation of selectivity in multimodal anion exchange systems: A priori prediction of protein retention and examination of mobile phase modifier effects

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