Use of Animal Models for Projection of Clinical Drug-Drug Interactions for Therapeutic Proteins

Author:

Kraynov Eugenia,Dowty Martin E.

Publisher

John Wiley & Sons, Inc.

Reference22 articles.

1. Predicting drug-drug interactions from in vitro drug metabolism data: challenges and recent advances;Obach;Curr Opin Drug Discov Devel,2009

2. Use of in vivo animal models to assess pharmacokinetic drug-drug interactions;Tang;Pharm Res,2010

3. P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer;Nedelcheva;Xenobiotica,1994

4. Species differences in metabolism and pharmacokinetics: are we close to an understanding?;Smith;Drug Metab Rev,1991

5. Cytochromes P450 in rats: structure, functions, properties and relevant human forms;Soucek;Xenobiotica,1992

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