The liver-gut microbiota axis modulates hepatotoxicity of tacrine in the rat-Reference-Cited by-同舟云学术

The liver-gut microbiota axis modulates hepatotoxicity of tacrine in the rat

Published:2017-11-19 Issue:1 Volume:67 Page:282-295
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Yip Lian Yee¹²,Aw Chiu Cheong³,Lee Sze Han¹,Hong Yi Shuen¹,Ku Han Chen¹,Xu Winston Hecheng¹,Chan Jessalyn Mei Xuan¹,Cheong Eleanor Jing Yi¹,Chng Kern Rei⁴,Ng Amanda Hui Qi⁴,Nagarajan Niranjan⁴,Mahendran Ratha⁵,Lee Yuan Kun⁶,Browne Edward R.³,Chan Eric Chun Yong¹⁷

Affiliation:

1. Department of Pharmacy, Faculty of Science; National University of Singapore; Singapore Singapore

2. Metabolomics, Bioprocessing Technology Institute; Singapore Singapore

3. GSK Neural Pathways DPU; Singapore Singapore

4. Computational and Systems Biology; Genome Institute of Singapore; Singapore Singapore

5. Department of Surgery, Yong Loo Lin School of Medicine; National University of Singapore; Singapore Singapore

6. Department of Microbiology, Yong Loo Lin School of Medicine; National University of Singapore; Singapore Singapore

7. Singapore Institute for Clinical Sciences; Singapore Singapore

Funder

Agency for Science, Technology, and Research (A*STAR) Biomedical Research Council

National University of Singapore

GSK R&D Centre in Singapore

Science and Engineering Research Council

Publisher

Wiley

Subject

Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.29327/fullpdf

Reference49 articles.

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4. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism;Clayton;Proc Natl Acad Sci U S A,2009

5. Metabolism of foreign compounds by gastrointestinal microorganisms;Scheline;Pharmacol Rev,1973

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