Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPARγ signaling pathways

Author:

Oyagbemi Ademola Adetokunbo1ORCID,Omobowale Temidayo Olutayo2,Ola-Davies Olufunke Eunice1,Asenuga Ebunoluwa Racheal3,Ajibade Temitayo Olabisi1,Adejumobi Olumuyiwa Abiola2,Arojojoye Oluwatosin Adetola4,Afolabi Jeremiah Moyinoluwa25,Ogunpolu Blessing Seun2,Falayi Olufunke Olubunmi6,Hassan Fasilat Oluwakemi1,Ochigbo Grace Onyeche6,Saba Adebowale Benard6,Adedapo Adeolu Alex6,Yakubu Momoh Audu7

Affiliation:

1. Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine; University of Ibadan; Ibadan Nigeria

2. Department of Veterinary Medicine, Faculty of Veterinary Medicine; University of Ibadan; Ibadan Nigeria

3. Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine; University of Benin; Benin Nigeria

4. Department of Biochemistry, Faculty of Sciences; Lead City University; Ibadan Nigeria

5. Cell Biology & Physiology track, Integrated Biomedical Sciences PhD; University of Tennessee Health Science Center; Memphis Tennessee

6. Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine; University of Ibadan; Ibadan Nigeria

7. Department of Environmental and Interdisciplinary Sciences; College of Science, Engineering and Technology, Vascular Biology Unit, Center for Cardiovascular Diseases, COPHS, Texas Southern University; Houston TX USA

Funder

Tertiary Education Trust Fund

National Research Foundation

Publisher

Wiley

Subject

Clinical Biochemistry,Molecular Medicine,General Medicine,Biochemistry

Reference70 articles.

1. Levels of fluoride in Niger seed (Guizotia abyssinica) cultivated in Ethiopia and Eritrea;Syume;Fluoride,2015

2. Caries-preventive effect of sodium fluoride mouthrinses: a systematic review of controlled clinical trials;Twetman;Acta. Odontologica. Scandinavica.,2004

3. Water fluoridation: a critical review of the physiological effects of ingested fluoride as a public health intervention;Peckham;Sci. World.,2014

4. Protective effect of quercetin against sodium fluoride induced oxidative stress in rat's heart;Nabavi;Food. Funct.,2012

5. Sodium fluoride induces renal inflammatory responses by activating NF-κB signaling pathway and reducing anti-inflammatory cytokine expression in mice;Luo;Oncotarget.,2017

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