Bioequivalence of Sarpogrelate in Healthy Chinese Subjects Under Fasting and Fed Conditions: A 4-Way Replicate Crossover Investigation by a Reference-Scaled Average Bioequivalence Approach-Reference-Cited by-同舟云学术

Bioequivalence of Sarpogrelate in Healthy Chinese Subjects Under Fasting and Fed Conditions: A 4-Way Replicate Crossover Investigation by a Reference-Scaled Average Bioequivalence Approach

Published:2018-10-16 Issue:6 Volume:8 Page:713-720
ISSN:2160-763X
Container-title:Clinical Pharmacology in Drug Development
language:en
Short-container-title:Clinical Pharmacology in Drug Development

Author:

Ding Y.H.¹,Liu B.²,Lou J.F.³,Sun J.X.¹,Wu M.¹,Zhu X.X.¹,Chen G.L.¹,Zhang H.¹,Li X.J.¹,Chen H.¹,Liu C.J.¹,Shen Z.W.⁴,Li C.Y.¹

Affiliation:

1. Phase 1 Clinical Unit, China-Frontage USA, First Hospital; Jilin University; Changchun Jilin China

2. Department of Hand Surgery, First Hospital; Jilin University; Changchun Jilin China

3. Department of Geriatrics, First Hospital; Jilin University; Changchun Jilin China

4. First Hospital; and Institute of Immunology; Jilin University; Changchun Jilin China

Funder

Tianjin Hongri Pharmaceutical

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpdd.624/fullpdf

Reference36 articles.

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3. Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease;Miyazaki;J Cardiovasc Pharmacol,2007

4. Platelet collagen receptors;Clemetson;Thromb Haemost,2001

5. Binding and functional affinity of sarpogrelate, its metabolite M-1 and ketanserin for human recombinant alpha-1-adrenoceptor subtypes;Israilova;Pharmacology,2002

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