In vivomeasurement of aldehyde dehydrogenase-2 activity in rat liver ethanol model using dynamic MRSI of hyperpolarized [1-13C]pyruvate

Author:

Josan Sonal,Xu Tao,Yen Yi-Fen1,Hurd Ralph2,Ferreira Julio,Chen Che-Hong3,Mochly-Rosen Daria3,Pfefferbaum Adolf,Mayer Dirk,Spielman Daniel

Affiliation:

1. Stanford University; Department of Radiology, Lucas MRI Center; Stanford; CA; USA

2. GE Healthcare Applied Sciences Laboratory; Menlo Park; CA; USA

3. Stanford University; School of Medicine, Department of Chemical and Systems Biology; Stanford; CA; USA

Publisher

Wiley

Subject

Spectroscopy,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference39 articles.

1. Alcohol and cardiovascular health: the razor-sharp double-edged sword;O'Keefe;J. Am. Coll. Cardiol.,2007

2. Involvement of acetaldehyde for full protection against alcoholism by homozygosity of the variant allele of mitochondrial aldehyde dehydrogenase gene in Asians;Peng;Pharmacogenetics,1999

3. A physiologically based model for ethanol and acetaldehyde metabolism in human beings;Umulis;Alcohol,2005

4. Disulfiram as a tool in the studies of metabolism of acetaldehyde in rats;Tottmar;Acta Pharmacol. Toxicol.,1976

5. The role of acetaldehyde in the actions of alcohol;Eriksson;Alcohol. Clin. Exp. Res.,2001

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