Eculizumab Dosing Regimen in Atypical HUS: Possibilities for Individualized Treatment

Author:

Volokhina E12,Wijnsma K1,van der Molen R2,Roeleveld N13,van der Velden T1,Goertz J2,Sweep F2,Brüggemann RJ4,Wetzels J5,van de Kar N1,van den Heuvel L126

Affiliation:

1. Department of Pediatric Nephrology; Amalia Children's Hospital, Radboud University Medical Center; Nijmegen The Netherlands

2. Department of Laboratory Medicine; Radboud University Medical Center; Nijmegen The Netherlands

3. Department of Health Evidence; Radboud University Medical Center; Nijmegen The Netherlands

4. Department of Pharmacy; Radboud University Medical Center; Nijmegen The Netherlands

5. Department of Nephrology; Radboud University Medical Center; Nijmegen The Netherlands

6. Department of Pediatrics; University Hospitals Leuven; Leuven Belgium

Funder

Nierstichting

European Renal Association - European Dialysis and Transplantation Association

European Society for Pediatric Nephrology

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference48 articles.

1. Atypical hemolytic-uremic syndrome;Noris;N. Engl. J. Med.,2009

2. Atypical hemolytic uremic syndrome;Loirat;Orphanet. J. Rare Dis.,2011

3. A new era in the diagnosis and treatment of atypical haemolytic uraemic syndrome;Westra;Neth. J. Med.,2012

4. Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults;Fremeaux-Bacchi;Clin. J. Am. Soc. Nephrol.,2013

5. Novel aspects of atypical haemolytic uraemic syndrome and the role of eculizumab;Verhave;Nephrol. Dial. Transplant,2014

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