Oroxylin A, a methylated metabolite of baicalein, exhibits a stronger inhibitory effect than baicalein on the CYP1B1‐mediated carcinogenic estradiol metabolite formation
Author:
Affiliation:
1. Clinical Pharmacokinetics LaboratoryChina Pharmaceutical University Nanjing China
Funder
National Natural Science Foundation of China
Publisher
Wiley
Subject
Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.6297
Reference30 articles.
1. Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids
2. Dietary flavonoids in cancer therapy and prevention: Substrates and inhibitors of cytochrome P450 CYP1 enzymes
3. Critical depurinating DNA adducts: Estrogen adducts in the etiology and prevention of cancer and dopamine adducts in the etiology and prevention of Parkinson's disease
4. Baicalein inhibits DMBA–DNA adduct formation by modulating CYP1A1 and CYP1B1 activities
5. Oroxylin A inhibits hypoxia-induced invasion and migration of MCF-7 cells by suppressing the Notch pathway
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Cellular and molecular mechanisms of oroxylin A in cancer therapy: Recent advances;European Journal of Pharmacology;2024-04
2. Dihydrotanshinone I-Induced CYP1 Enzyme Inhibition and Alteration of Estradiol Metabolism;Drug Metabolism and Disposition;2023-12-15
3. Functional variant rs10175368 which affects the expression of CYP1B1 plays a protective role against breast cancer in a Chinese Han population;European Journal of Cancer Prevention;2023-04-10
4. Promising Role of the Scutellaria baicalensis Root Hydroxyflavone–Baicalein in the Prevention and Treatment of Human Diseases;International Journal of Molecular Sciences;2023-03-01
5. Effects of xenobiotics on CYP1 enzyme-mediated biotransformation and bioactivation of estradiol;Drug Metabolism Reviews;2023-02-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3