Concomitant blockade of A2AR and CTLA‐4 by siRNA‐loaded polyethylene glycol‐chitosan‐alginate nanoparticles synergistically enhances antitumor T‐cell responses

Author:

Ghasemi‐Chaleshtari Mitra1,Kiaie Seyed Hossein23,Irandoust Mahzad4,Karami Hadis5,Nabi Afjadi Mohsen6,Ghani Sepideh7ORCID,Aghaei Vanda Nasimeh4,Ghaderi Sede Mohammad Javad8,Ahmadi Armin9,Masjedi Ali4ORCID,Hassannia Hadi10,Atyabi Fatemeh11ORCID,Hojjat‐Farsangi Mohammad12,Namdar Afshin13,Ghalamfarsa Ghasem14,Jadidi‐Niaragh Farhad1516ORCID

Affiliation:

1. Department of Clinical Biochemistry, School of Medicine Babol University of Medical Sciences Babol Mazandaran Iran

2. Nano Drug Delivery Research Center Kermanshah University of Medical Sciences Kermanshah Iran

3. Student Research Committee Tabriz University of Medical Sciences Tabriz Iran

4. Drug Applied Research Center Tabriz University of Medical Sciences Tabriz Iran

5. Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology University of Isfahan Isfahan Iran

6. Department of Biochemistry, Faculty of Biological Sciences University of Tarbiat Modares Tehran Iran

7. Student Research Committee, Department of Biotechnology, School of Advanced Technologies in Medicine Shahid Beheshti University of Medical Sciences Tehran Iran

8. Department of Nanotechnology, School of Advanced Technologies in Medicine Tehran University of Medical Sciences Tehran Iran

9. Department of Chemical and Materials Engineering The University of Alabama in Huntsville Huntsville Alabama

10. Immunogenetic Research Center, Faculty of Medicine Mazandaran University of Medical Sciences Sari Iran

11. Nanotechnology Research Centre, Faculty of Pharmacy Tehran University of Medical Sciences Tehran Iran

12. Bioclinicum, Department of Oncology‐Pathology Karolinska Institute Stockholm Sweden

13. Department of Oncology, Cross Cancer Institute The University of Alberta Edmonton Alberta Canada

14. Cellular and Molecular Research Center Yasuj University of Medical Sciences Yasuj Iran

15. Immunology Research Center Tabriz University of Medical Sciences Tabriz Iran

16. Department of Immunology, School of Medicine Tabriz University of Medical Sciences Tabriz Iran

Funder

Tabriz University of Medical Sciences

Iran National Science Foundation

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

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