Assessment of OATP transporter-mediated drug-drug interaction using physiologically-based pharmacokinetic (PBPK) modeling - a case example-Reference-Cited by-同舟云学术

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Assessment of OATP transporter-mediated drug-drug interaction using physiologically-based pharmacokinetic (PBPK) modeling - a case example

Published:2018-11 Issue:9 Volume:39 Page:420-430
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm Drug Dispos

Author:

Chen Yuan¹^ORCID,Zhu Rui²,Ma Fang¹,Mao Jialin¹,Chen Eugene C.¹,Choo Edna F.¹,Sahasranaman Srikumar²,Liu Lichuan²

Affiliation:

1. Drug Metabolism and Pharmacokinetics; Genentech Inc.; South San Francisco CA 94080 USA

2. Clinical Pharmacology; Genentech Inc.; South San Francisco CA 94080 USA

Funder

Genentech

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.2159/fullpdf

Reference43 articles.

1. Cyclosporine A, but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin;Amundsen;Drug Metabolism and Disposition,2010

2. Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients;Asberg;Drugs,2003

3. Effects of ezetimibe on cyclosporine pharmacokinetics in healthy subjects;Bergman;Journal of Clinical Pharmacology,2006

4. Effect of multidrug resistance-reversing agents on transporting activity of human canalicular multispecific organic anion transporter;Chen;Molecular Pharmacology,1999

5. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction;Cheng;Biochemical Pharmacology,1973

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2. Physiologically-Based Pharmacokinetic Modeling for Drugs Cleared by Non-Cytochrome P450 Enzymes: State-of-the-Art and Future Perspectives;Drug Metabolism and Disposition;2023-10-25

3. The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans;Pharmacology & Therapeutics;2022-10

4. The Next Frontier in ADME Science: Predicting Transporter-Based Drug Disposition, Tissue Concentrations and Drug-Drug Interactions in Humans;SSRN Electronic Journal;2022

5. Biomarker‐Informed Model‐Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug‐Drug Interactions;Clinical Pharmacology & Therapeutics;2021-10-22

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