An improved ultra‐high‐performance liquid chromatography–tandem mass spectrometric method for the quantitation of dexmedetomidine in small volume of pediatric plasma-Reference-Cited by-同舟云学术

An improved ultra‐high‐performance liquid chromatography–tandem mass spectrometric method for the quantitation of dexmedetomidine in small volume of pediatric plasma

Published:2019-02-07 Issue:6 Volume:33 Page:e4487
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Moorthy Ganesh S.¹²^ORCID,Vedar Christina¹,Moorthy Ahila S.¹,Prodell Janice L.¹²,Zuppa Athena F.¹²

Affiliation:

1. Children's Hospital of PhiladelphiaUniversity of Pennsylvania Philadelphia PA USA

2. Department of Anesthesiology and Critical Care Medicine, Center for Clinical Pharmacology USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4487

Reference10 articles.

1. Development of a stable isotope dilution UPLC-MS/MS method for quantification of dexmedetomidine in a small amount of human plasma

2. Simultaneous quantitation of dexmedetomidine and glucuronide metabolites(G-Dex-1 and G-Dex-2) in human plasma utilizing liquid chromatography with tandem mass spectrometric detection

3. Sensitive and specific liquid chromatography–tandem mass spectrometric method for the quantitation of dexmedetomidine in pediatric plasma

4. Determination of dexmedetomidine in human plasma using high performance liquid chromatography coupled with tandem mass spectrometric detection: Application to a pharmacokinetic study

5. Determination of dexmedetomidine in children’s plasma by ultra-performance liquid chromatography tandem mass spectrometry and application to pharmacokinetic study

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1. Simultaneous detection of a panel of nine sedatives and metabolites in plasma from critically ill pediatric patients via UPLC-MS/MS;Journal of Pharmaceutical and Biomedical Analysis;2022-09

2. Dexmedetomidine in Children on Extracorporeal Membrane Oxygenation: Pharmacokinetic Data Exploration Using Previously Published Models;Frontiers in Pediatrics;2022-06-27

3. Dose Escalation Pharmacokinetic Study of Intranasal Atomized Dexmedetomidine in Pediatric Patients With Congenital Heart Disease;Anesthesia & Analgesia;2022-04-21

4. Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial): A Randomized Controlled Trial: Background, Aims and Study Protocol;Frontiers in Pain Research;2021-12-07

5. Sequestration of Dexmedetomidine in Ex Vivo Cardiopulmonary Bypass Circuits;ASAIO Journal;2021-08-03