The impact of donating milk on the health of milk donors and their infants: A systematic review and meta‐analysis protocol

Author:

Berg Alaina1ORCID,Rani Uzma2,Colaizy Tarah3,Smith Abigail4,Evans James4,Murad Mohammad H.5,Bhutta Zulfiqar A.6789,Imdad Aamer10ORCID

Affiliation:

1. The University of Iowa Carver College of Medicine Iowa City Iowa USA

2. Stead Family Department of Pediatrics, Division of Neonatology University of Iowa Carver College of Medicine Iowa City Iowa USA

3. Stead Family Department of Pediatrics, Division of General Pediatrics University of Iowa Carver College of Medicine Iowa City Iowa USA

4. Health Sciences Library State University of New York Upstate Medical University Syracuse New York USA

5. Department of Internal Medicine, Division of Preventive, Occupational and Aerospace Medicine Mayo Clinic Rochester Minnesota USA

6. Centre for Global Child Health Hospital for Sick Children Toronto Ontario Canada

7. Centre of Excellence in Women and Child Health Aga Khan University Karachi Pakistan

8. Institute for Global Health and Development Aga Khan University Karachi Pakistan

9. Department of Nutrition, Joannah and Brian Lawson Centre for Child Nutrition University of Toronto Toronto Ontario Canada

10. Stead Family Department of Pediatrics, Division of Gastroenterology, Hepatology, Pancreatology, and Nutrition University of Iowa Iowa City Iowa USA

Abstract

AbstractObjectivesBreast milk is the recommended nutritional source for newborns and has been associated with decreased morbidity in low‐birth‐weight and preterm infants. In situations where breast milk is not available, donor breast milk is an alternative. Milk banking is becoming increasingly common worldwide to meet this need. Although the benefits of donor breast milk for the recipient infant are well established, the health impact on the breast milk donor and the infant of the breast milk donor is an area of current research. We aim to synthesize and evaluate the available evidence regarding the impact of donating breast milk on the health, lactation, and well‐being of the breast milk donor, and the health and growth of the infant of the breast milk donor.MethodsWe will search electronic databases, grey literature, and the websites of relevant international organizations. We will include studies that involve lactating women and their infants, healthy or with health conditions, who donate breast milk, without restrictions on study date, language, or study design. If sufficient homogeneity exists between studies, we will complete meta‐analyses. We will evaluate the risk of bias using the Risk of Bias tool or the Cochrane Risk of Bias in Non‐Randomized Studies tool. We will evaluate the overall certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach.ConclusionIn this systematic review and meta‐analysis, we will summarize the current literature regarding the effects of human milk donation on human milk donors and their infants.

Publisher

Wiley

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