Fulvanines J−K, two rare lactam pyrrole alkaloids from Hemerocallis fulva

Author:

Lei Ya‐E.1,Wang Qian1,Yaermaimaiti Saimijiang1,Ma Zi‐Hui1,Li Miao‐Miao1,Lu Yan2,Chen Dao‐Feng2,Wang Qi1ORCID

Affiliation:

1. Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, School of Pharmacy Shihezi University Shihezi 832002 P. R. China

2. Department of Pharmacognosy, School of Pharmacy Fudan University Shanghai 201203 P. R. China

Abstract

AbstractTwo rare jatropham lactam derivatives, named as fulvanines J−K (12), together with six known pyrrole alkaloids, 5,5′‐oxydi(3‐methyl‐3‐pyrrolin‐2‐one) (3), (−)‐5‐hydroxy‐3‐methyl‐3‐pyrrolin‐2‐one (jatropham) (4), (±)‐5‐O‐methyljatropham (5), perlolyrine (6), butyl‐2‐formyl‐5‐(hydroxymethyl)‐1H‐pyrrole‐1‐butanoate (7), and hemerocallisamine II (8), were isolated from the flower of Hemerocallis fulva. Their structures were elucidated on the basis of spectroscopic methods and compared with the NMR spectra data in the literature. All compounds were evaluated for their anti‐complementary activity in vitro, and compounds 1, 4, and 6 exhibited anti‐complement effect with CH50 values from 0.61 to 1.42 mM.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Reference19 articles.

1. Editorial Board of Traditional Chinese Medicine of the State Administration of Traditional Chinese Medicine Chinese herbs Shanghai Science and Technology Press1999 22 101.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3