Affiliation:
1. Rede Nordeste de Biotecnologia – RENORBIO Universidade Estadual do Ceará Av. Dr. Silas Munguba, 1700 – Campus do Itaperi 60714-903 Fortaleza Ceará Brasil
2. Departamento de Química Biológica Laboratório de Pesquisa de Produtos Naturais Universidade Regional do Cariri Rua Coronel Antônio Luíz, 1161 – Pimenta 63105–010 Crato Ceará Brasil
Abstract
AbstractQuinones are natural products widely distributed in nature, which are involved in stages of several vital biological processes, with mostly having a variety of pharmacological properties. The main groups comprising most of these compounds are benzoquinones, naphthoquinones, anthraquinones, and phenanthraquinones. Quinone isolation has been a focus of study around the world in recent years; for this reason, this study approaches the junction of natural quinones identified by 13C Nuclear Magnetic Resonance (NMR) spectroscopic analytical techniques. The methodology used to obtain the data collected articles from various databases on quinones from 2000 to 2022. As a result, 137 compounds were selected, among which 70 were characterized for the first time in the period investigated; moreover, the study also discusses the biosynthetic pathways of quinones and the pharmacological activities of the compounds found, giving an overview of the various applications of these compounds.
Funder
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Subject
Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering