Flavonoids and Triterpenoids Isolated From the Ethyl Acetate Extract of <i>M. quadrangulata</i> Leaves-Reference-Cited by-同舟云学术

Flavonoids and Triterpenoids Isolated From the Ethyl Acetate Extract of M. quadrangulata Leaves

Published:2024-06-24 Issue:7 Volume:21 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

de Aguilar Mariana Guerra¹^ORCID,Veríssimo Morais Quintão Sandy¹,Camargo Karen Caroline¹,Pains Duarte Lucienir¹,Vasconcelos Laisa Resende²,de Magalhães José Carlos²,de Sousa Grasiely Faria¹^ORCID

Affiliation:

1. Departamento de Química Universidade Federal de Minas Gerais Avenida Presidente Antônio Carlos, 6627, Pampulha Belo Horizonte MG, 31270-901 Brazil

2. Laboratório de Virologia e Tecnologia celular Departamento de Química, Biotecnologia e Engenharia de Bioprocessos, Campus Alto Paraopeba Universidade Federal de São João del-Rei Ouro Branco MG, 36497-899 Brazil

Abstract

AbstractThe new flavonoid (−)‐4’‐O‐methylepicatechin 5‐O‐β‐D‐glucopyranoside (1), along with four known triterpenes (2‐5), a steroid (6), and a flavonoid (7) were isolated from the ethyl acetate extract of Maytenus quadrangulata leaves. The chemical structures of the isolated compounds were determined through analysis of 1D NMR (1H and 13C) spectroscopic data, in addition to 2D NMR and spectrometric (MS) data for compound 1. This is the first report of the isolation of daucosterol (6) and (−)‐4’‐O‐methylepigallocatechin (7) from this species. Compounds 1 and 7 were evaluated against the bacteria Staphylococcus aureus and Klebsiella pneumoniae, but neither exhibited activity even at the highest concentration tested.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202400636

Reference33 articles.

1. Effects of Plants and Isolates of Celastraceae Family on Cancer Pathways

2. A Review of the Ethnopharmacology, Phytochemistry and Pharmacology of Plants of the Maytenus Genus

3. Pharmacological potential of Maytenus species and isolated constituents, especially tingenone, for treatment of painful inflammatory diseases

4. Phytochemicals and biological activities of species from the genus Maytenus

5. In vivo antiplasmodial and toxicological effect of Maytenus senegalensis traditionally used in the treatment of malaria in Tanzania