A New Monoterpene Alkaloid from <i>Incarvillea sinensis</i> with Migration Inhibitory Activity on Cancer Cell-Reference-Cited by-同舟云学术

A New Monoterpene Alkaloid from Incarvillea sinensis with Migration Inhibitory Activity on Cancer Cell

Published:2023-03-24 Issue:4 Volume:20 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

Song Weirong¹²,Zhang Jie²³,Zhao Pengxiang¹²,Huang Yongchun¹²,Zhang Shoude¹

Affiliation:

1. State Key Laboratory of Plateau Ecology and Agriculture Qinghai University 251# Ningda Road Xining 810016 Qinghai China

2. Department of Pharmacy Medical College of Qinghai University 16# Kunlun Road Xining 810016 Qinghai China

3. Qinghai University Affiliated Hospital 29# Tongren Road Xining 810016 Qinghai China

Abstract

AbstractA novel monoterpene alkaloid, named incarvine G, was isolated from the Incarvillea sinensis Lam. Its chemical structure was elucidated using comprehensive spectroscopic methods. Incarvine G is an ester compound comprised of a monoterpene alkaloid and glucose. This compound showed evident inhibition on cell migration, invasion, and cytoskeleton formation of human MDA‐MB‐231 with low cytotoxicity.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202201203

Reference16 articles.

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2. A novel macrocyclic spermine alkaloid fromIncarvillea sinensis

3. Structure-Antinociceptive Activity Studies of Incarvillateine, a Monoterpene Alkaloid from Incarvillea sinensis

4. A Monoterpene Alkaloid from Incarvillea sinensis

5. Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis and possible involvement of the adenosine system

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