Affiliation:
1. Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine Postgraduate Training Base of Guangzhou University of Chinese Medicine 518104 Shenzhen China
2. Key Laboratory of Marine Genetic Resources Third Institute of Oceanography, Ministry of Natural Resources 184 Daxue Road Xiamen 361005 China
Abstract
AbstractThree new C10 and C12 aliphatic δ‐lactones (1–3), three new fatty acid methyl esters (4–6), and eight known compounds (7–14) were isolated from the marine Aureobasidium sp. LUO5. Their structures were established by detailed analyses of the NMR, HRESIMS, optical rotation, and ECD data. All isolates were tested for their inhibitory effects on nitric oxide production in LPS‐induced BV‐2 cells. Notably, compound 4 displayed the strongest inhibitory effect with the IC50 value of 120.3 nM.
Funder
Xiamen Southern Oceanographic Center