Insight into the Therapeutic Potential of a Bicyclic Hydroxypyridone Compound 2‐[(2,4‐Dichlorophenyl)methyl]‐7‐hydroxy‐1,2,3,4‐tetrahydro‐8 H ‐pyrido[1,2‐ a ]pyrazin‐8‐one as COMT Inhibitor in the Treatment of Parkinson's Disease: A Molecular Dynamic Simulation Approach-Reference-Cited by-同舟云学术

Insight into the Therapeutic Potential of a Bicyclic Hydroxypyridone Compound 2‐[(2,4‐Dichlorophenyl)methyl]‐7‐hydroxy‐1,2,3,4‐tetrahydro‐8 H ‐pyrido[1,2‐ a ]pyrazin‐8‐one as COMT Inhibitor in the Treatment of Parkinson's Disease: A Molecular Dynamic Simulation Approach

Published:2021-08-09 Issue:9 Volume:18 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chem. Biodiversity

Author:

Subair Temitayo I.¹,Akawa Oluwole B.¹²,Soremekun Opeyemi S.¹,Olotu Fisayo A.¹,Soliman Mahmoud E. S.¹^ORCID

Affiliation:

1. Molecular Bio-computation and Drug Design Laboratory School of Health Sciences University of KwaZulu-Natal Westville Campus Durban 4001 South Africa

2. Department of Pharmacology and Therapeutics College of Medicine and Health Sciences Afe Babalola University Ado Ekiti State Nigeria

Funder

Inyuvesi Yakwazulu-Natali

National Research Foundation

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202100204

Reference42 articles.

1. Cheminformatics and virtual screening studies of COMT inhibitors as potential Parkinson’s disease therapeutics