Synthesis of silver nanoparticles from Ganoderma species and their activity against Multi drug resistant pathogens.

Author:

Syed Iffraz Ali1,Ahmad Junaid2,Butt Sadia3,Ullah Amin4,Ahmed Iftikhar5,Niaz Zeeshan1,Hayat Shubana1,Ashique Sumel6,Zengin Gokhan7,Farid Arshad8

Affiliation:

1. Hazara University microbiology Mansehra. Mansehra. PAKISTAN

2. University of Rome Tor Vergata: Universita degli Studi di Roma Tor Vergata microbiology rome rome ITALY

3. Shaheed Benazir Bhutto Women University microbiology Peshawar Peshawar PAKISTAN

4. Abasyn University Health Peshawar Peshawar PAKISTAN

5. Gomal University Biochemisty Gomal Gomal PAKISTAN

6. Pandaveswar University Pharmaceutics West Bengal West Bengal INDIA

7. Selcuk Universitesi biology campus 42250 Konya TURKEY

8. Gomal University Biotechnology Gomal Gomal PAKISTAN

Abstract

. The present antimicrobics have been unsuccessful in curing infections; several investigators have determined their struggles towards natural resources i.e., plants along with mushrooms as a source of new bioactive complexes. The goal of the research was to molecularly identify and characterize the mushrooms collected in order to build a phylogenetic tree and antibacterial activity was tested using raw, aqueous extract, along with silver nanoparticles. For classification of AgNPs numerous methods were utilized i‐e XRD, FTIR, UV‐VIS, and SEM analysis. Outcomes of the raw extract, aqueous extract, as well as AgNPs presented antibacterial action versus all tested bacteria. . Furthermore, these AgNPs exhibit potential activity against P. aeruginosa, A. baumannii (ZOI 24mm), S. aureus, (ZOI 23mm) K. pneumonia (ZOI 20mm), and E. fecalis (ZOI 10mm), enhancing the efficacy of these NPs in biological applications. These outcomes determined that AgNPs can destroy MDR bacteria as well as it can be employed in therapeutic devices and an antibacterial vehicle for an array of biotic applications. Corresponding to these results, AgNPs of small sizes have potency to be vigorously used in the creation of nano‐ medicines.

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

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