Chitosan and Chitooligosaccharides: Antifungal Potential and Structural Insights-Reference-Cited by-同舟云学术

Chitosan and Chitooligosaccharides: Antifungal Potential and Structural Insights

Published:2024-05-09 Issue:6 Volume:21 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

de Azevedo Mayara Itala Geronimo¹,Souza Pedro Filho Noronha¹²³⁴,Monteiro Júnior José Edvar⁵,Grangeiro Thalles Barbosa⁵

Affiliation:

1. Department of Biochemistry and Molecular Biology Federal University of Ceará Fortaleza Ceará Brazil

2. Pharmacogenetics Laboratory Drug Research and Development Center (NPDM) Federal University of Ceará Fortaleza CE, 60430-275 Brazil

3. National Institute of Science and Technology in Human Pathogenic Fungi São Paulo Brazil

4. Visiting Researcher at the Cearense Foundation to Support Scientific and Technological Development Foratelza Ceará Brazil

5. Laboratory of Molecular Genetics Department of Biology Science Center Federal University of Ceará Fortaleza Ceará Brazil

Abstract

AbstractChitosan is a cationic polysaccharide derived from chitin deacetylation. This polysaccharide and its oligosaccharides have many biological activities and can be used in several fields due to their favorable characteristics, such as biodegradability, biocompatibility, and nontoxicity. This review aims to explore the antifungal potential of chitosan and chitooligosaccharides along with the conditions used for the activity and mechanisms of action they use to kill fungal cells. The sources, chemical properties, and applications of chitosan and chitooligosaccharides are discussed in this review. It also addresses the threat fungi pose to human health and crop production and how these saccharides have proven to be effective against these microorganisms. The cellular processes triggered by chitosan and chitooligosaccharides in fungal cells, and prospects for their use as potential antifungal agents are also examined.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202400044

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