Affiliation:
1. Pharmaceutics & Pharmacokinetics Division CSIR-Central Drug Research Institute Lucknow Uttar Pradesh 226031 India
2. Academy of Scientific & Innovative Research (AcSIR) Ghaziabad Uttar Pradesh 201002 India
3. Department of Chemistry Government P. G. College Guna Madhya Pradesh 473001 India
Abstract
AbstractPirfenidone, initially indicated for lung fibrosis, has gone beyond its original purpose, and shown promise in eye care. This detailed review tracks its evolution from lung treatment to aiding eye healing as evidenced by published literature. Pirfenidone's multifaceted attributes extend to mitigating corneal fibrosis, inflammation, and trauma. Through rigorous investigations, its efficacy emerges in diabetic retinopathy, macular degeneration, and postoperative glaucoma interventions. As an unheralded protagonist, pirfenidone reshapes ocular care paradigms, inviting renewed research opportunities.
Cited by
6 articles.
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